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Mechanics of the cell /

David Boal.

Book Cover
Author: Boal, David H.
Vernacular: 6.5.3 Model results for G'(ω) -- 6.6 Rheology of cytoskeletal components -- 6.6.1 Storage and loss moduli -- 6.6.2 Measurements of viscoelasticity -- 6.6.3 Chain densities in actin networks -- 6.6.4 Cross-linked actin networks -- 6.6.5 Actin solutions -- 6.6.6 Actin filaments at high density -- 6.6.7 Intermediate filament and microtubule solutions -- 6.6.8 Other measurements of soft networks -- Summary -- Problems -- Applications -- Formal development and extensions -- PART II MEMBRANES -- 7 Biomembranes -- 7.1 Membranes, walls and lamina -- 7.2 Self-assembly of amphiphiles -- 7.2.1 Spherical micelles -- 7.2.2 Cylindrical micelles -- 7.2.3 Bilayers -- 7.2.4 Inverted micelles -- 7.2.5 Amphiphiles in the cell -- 7.3 Bilayer compression resistance -- 7.3.1 Experimental measurements of KA and KV -- 7.3.2 Benchmark estimates of KA -- 7.3.3 Rupture tension -- 7.4 Bilayer bending resistance -- 7.4.1 Radius of curvature -- 7.4.2 Experimental measurements of κb -- 7.4.3 Interpretation of κb -- 7.5 Edge energy -- 7.5.1 Vesicle formation: edge energy vs. bending energy -- 7.5.2 Membrane rupture: edge energy vs. tension -- 7.5.3 Measured edge tensions -- 7.6 Cell walls and sheaths -- 7.6.1 Basal lamina -- 7.6.2 Plant cell wall -- Summary -- Problems -- Applications -- Formal development and extensions -- 8 Membrane undulations -- 8.1 Thermal fluctuations in membrane shape -- 8.2 Mathematics of curvature -- 8.3 Membrane bending and persistence length -- 8.3.1 Fourier components of -- 8.3.2 Fourier components and the equipartition theorem -- 8.3.3 Persistence length -- 8.4 Scaling of polymers and membranes -- 8.4.1 Membranes without self-avoidance -- 8.4.2 Flory scaling of polymers and membranes -- (i) Short distances -- (ii) Long distances -- 8.4.3 Fluid and polymerized membranes -- 8.4.4 Effects of pressure and attraction.
Cover -- Mechanics of the Cell -- Title -- Copyright -- Contents -- Preface -- List of symbols -- 1 Introduction to the cell -- 1.1 Designs for a cell -- 1.1.1 Thin membranes for isolating a cell's contents -- 1.1.2 Networks for tensile strength -- 1.1.3 Composite structures for materials efficiency -- 1.1.4 Internal organization for efficient operation -- 1.1.5 Materials to match the expected usage -- 1.2 Cell shapes, sizes and structures -- 1.2.1 Mycoplasmas and bacteria -- 1.2.2 Plant and animal cells -- 1.3 Biomaterials: soft strings and sheets -- 1.3.1 Soft filaments -- 1.3.2 Soft sheets -- 1.3.3 Soft vs. hard: entropy vs. energy -- 1.4 Forces inside and outside the cell -- Summary -- 2 Soft materials and fluids -- 2.1 Fluctuations at the cellular scale -- 2.2 Movement in a viscous fluid -- 2.2.1 Translational drag -- 2.2.2 Rotational drag -- 2.2.3 Reynolds number -- 2.3 Random walks -- 2.4 Diffusion -- 2.4.1 Densities and fluxes -- 2.5 Fluctuations and correlations -- Summary -- Problems -- Applications -- Formal development and extensions -- PART I RODS AND ROPES -- 3 Polymers -- 3.1 Polymers and simple biofilaments -- 3.2 Mathematical description of flexible rods -- 3.2.1 Arc length and curvature -- 3.2.2 Bending energy of a thin rod -- 3.2.3 Directional fluctuations and persistence length -- 3.3 Sizes of polymer chains -- 3.3.1 Ideal chains and filaments -- 3.3.2 Self-avoiding linear chains -- 3.3.3 Branched polymers -- 3.3.4 Collapsed chains -- 3.4 Entropic elasticity -- 3.4.1 Random chain in three dimensions -- 3.4.2 Entropic elasticity -- 3.4.3 Highly stretched chains -- 3.5 Buckling -- 3.6 Measurements of bending resistance -- 3.6.1 Measurements of persistence length -- 3.6.2 ξp and Young's modulus -- 3.6.3 Filament configurations in the cell -- 3.6.4 Filamentous cells -- Summary -- Problems -- Applications.
Formal development and extensions -- 4 Complex filaments -- 4.1 The structure of complex filaments -- 4.2 Torsion, twist and writhe -- 4.2.1 Twist without curvature -- 4.2.2 Twist with curvature -- 4.2.3 Twist and writhe -- 4.3 Measurements of torsional rigidity -- 4.3.1 DNA -- 4.3.2 F-actin -- 4.3.3 Microtubules -- 4.3.4 Other filaments -- 4.4 Stretching of folded polymers -- (1) Spectrin -- (2) Ubiquitin -- (3) Tenascin -- (4) Titin -- 4.5 Protein and RNA folding -- concepts -- (1) α-helices -- (2) β-sheets -- 4.6 Models for polymer folding -- Summary -- Problems -- Applications -- Formal development and extensions -- 5 Two-dimensional networks -- 5.1 Soft networks in the cell -- 5.2 Elasticity in two dimensions -- 5.2.1 Deformations and the strain tensor -- 5.2.2 Forces and the stress tensor -- 5.2.3 Elastic moduli -- 5.2.4 Six-fold networks in 2D -- 5.2.5 Four-fold networks in 2D -- 5.2.6 Networks of springs -- 5.3 Isotropic networks -- 5.3.1 Six-fold spring networks under stress -- 5.3.2 Six-fold spring networks at non-zero temperature -- 5.4 Networks with low coordination number -- 5.5 Membrane-associated networks -- 5.5.1 Measured network elasticity -- 5.5.2 Interpretation of measurements -- Summary -- Problems -- Applications -- Formal development and extensions -- 6 Three-dimensional networks -- 6.1 Networks of biological rods and ropes -- 6.2 Elasticity in three dimensions -- 6.2.1 Strain and stress -- 6.2.2 Elastic moduli -- 6.2.3 Young's modulus and Poisson's ratio -- 6.2.4 Spring network with cubic symmetry -- 6.3 Entropic networks -- 6.3.1 Construction of random chain networks -- 6.3.2 Deformation of the network -- 6.3.3 Entropy change under deformation -- 6.3.4 Elastic moduli -- 6.4 Network percolation and failure -- 6.5 Semiflexible polymer solutions -- 6.5.1 Classification of polymer solutions -- 6.5.2 Storage and loss moduli.
Published: Cambridge ; Cambridge University Press, 2012.
Edition: 2nd ed.
Topics: Cells - Mechanical properties. | Physical biochemistry. | Cell Physiological Phenomena. | SCIENCE - Life Sciences - Biophysics. | SOCIAL SCIENCE - Anthropology - Physical. | Biomechanik
Regions: Celle
Genres: Electronic books.
Online Access: Cambridge Core - Full text online
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100 1 |aBoal, David H.,|eauthor.
245 10|aMechanics of the cell /|cDavid Boal.
250 |a2nd ed.
260 |aCambridge ;|aNew York :|bCambridge University Press,|c2012.
300 |a1 online resource (xiv, 608 pages) :|billustrations (some color)
336 |atext|btxt|2rdacontent
337 |acomputer|bc|2rdamedia
338 |aonline resource|bcr|2rdacarrier
504 |aIncludes bibliographical references (pages 565-602) and index.
505 00|g1.|tIntroduction to the cell --|g2.|tSoft materials and fluids --|g3.|tPolymers --|g4.|tComplex filaments --|g5.|tTwo-dimensional networks --|g6.|tThree-dimensional networks --|g7.|tBiomembranes --|g8.|tMembrane undulations --|g9.|tIntermembrane and electrostatic forces --|g10.|tThe simplest cells --|g11.|tDynamic filaments --|g12.|tGrowth and division --|g13.|tSignals and switches --|gappendix A.|tAnimal cells and tissues --|gappendix B.|tThe cell's molecular building blocks --|gappendix C.|tElementary statistical mechanics --|gappendix D.|tElasticity.
520 |a"Exploring the mechanical features of biological cells, including their architecture and stability, this textbook is a pedagogical introduction to the interdisciplinary fields of cell mechanics and soft matter physics from both experimental and theoretical perspectives. This second edition has been greatly updated and expanded, with new chapters on complex filaments, the cell division cycle, the mechanisms of control and organization in the cell, and fluctuation phenomena. The textbook is now in full color which enhances the diagrams and allows the inclusion of new microscopy images. With more than 300 end-of-chapter exercises exploring further applications, this textbook is ideal for advanced undergraduate and graduate students in physics and biomedical engineering. A website hosted by the author contains extra support material, diagrams and lecture notes, and is available at www.cambridge.org/9780521130691"--|cProvided by publisher.
588 0 |aPrint version record.
650 0|aCells|xMechanical properties.
650 0|aPhysical biochemistry.
650 12|aCell Physiological Phenomena.|0(DNLM)D002468
650 7|aSCIENCE|xLife Sciences|xBiophysics.|2bisacsh
650 7|aSOCIAL SCIENCE|xAnthropology|xPhysical.|2bisacsh
650 7|aCells|xMechanical properties.|2fast|0(OCoLC)fst00850266
650 7|aPhysical biochemistry.|2fast|0(OCoLC)fst01062368
650 7|aBiomechanik|2gnd|0(DE-588)4006880-8
651 7|aCelle|2gnd|0(DE-588)4009657-9
655 4|aElectronic books.
776 08|iPrint version:|aBoal, David H.|tMechanics of the cell.|b2nd ed.|dCambridge ; New York : Cambridge University Press, 2012|z9780521113762|w(DLC) 2011038238|w(OCoLC)754389836
852 8 |beresour-nc|hOnline Resource|t1|zAccessible anywhere on campus or with UIUC NetID
856 40|3Cambridge Core - Full text online|uhttp://www.library.illinois.edu/proxy/go.php?url=https://doi.org/10.1017/CBO9781139022217
880 8 |6505-00|a6.5.3 Model results for G'(ω) -- 6.6 Rheology of cytoskeletal components -- 6.6.1 Storage and loss moduli -- 6.6.2 Measurements of viscoelasticity -- 6.6.3 Chain densities in actin networks -- 6.6.4 Cross-linked actin networks -- 6.6.5 Actin solutions -- 6.6.6 Actin filaments at high density -- 6.6.7 Intermediate filament and microtubule solutions -- 6.6.8 Other measurements of soft networks -- Summary -- Problems -- Applications -- Formal development and extensions -- PART II MEMBRANES -- 7 Biomembranes -- 7.1 Membranes, walls and lamina -- 7.2 Self-assembly of amphiphiles -- 7.2.1 Spherical micelles -- 7.2.2 Cylindrical micelles -- 7.2.3 Bilayers -- 7.2.4 Inverted micelles -- 7.2.5 Amphiphiles in the cell -- 7.3 Bilayer compression resistance -- 7.3.1 Experimental measurements of KA and KV -- 7.3.2 Benchmark estimates of KA -- 7.3.3 Rupture tension -- 7.4 Bilayer bending resistance -- 7.4.1 Radius of curvature -- 7.4.2 Experimental measurements of κb -- 7.4.3 Interpretation of κb -- 7.5 Edge energy -- 7.5.1 Vesicle formation: edge energy vs. bending energy -- 7.5.2 Membrane rupture: edge energy vs. tension -- 7.5.3 Measured edge tensions -- 7.6 Cell walls and sheaths -- 7.6.1 Basal lamina -- 7.6.2 Plant cell wall -- Summary -- Problems -- Applications -- Formal development and extensions -- 8 Membrane undulations -- 8.1 Thermal fluctuations in membrane shape -- 8.2 Mathematics of curvature -- 8.3 Membrane bending and persistence length -- 8.3.1 Fourier components of -- 8.3.2 Fourier components and the equipartition theorem -- 8.3.3 Persistence length -- 8.4 Scaling of polymers and membranes -- 8.4.1 Membranes without self-avoidance -- 8.4.2 Flory scaling of polymers and membranes -- (i) Short distances -- (ii) Long distances -- 8.4.3 Fluid and polymerized membranes -- 8.4.4 Effects of pressure and attraction.
880 0 |6505-00|aCover -- Mechanics of the Cell -- Title -- Copyright -- Contents -- Preface -- List of symbols -- 1 Introduction to the cell -- 1.1 Designs for a cell -- 1.1.1 Thin membranes for isolating a cell's contents -- 1.1.2 Networks for tensile strength -- 1.1.3 Composite structures for materials efficiency -- 1.1.4 Internal organization for efficient operation -- 1.1.5 Materials to match the expected usage -- 1.2 Cell shapes, sizes and structures -- 1.2.1 Mycoplasmas and bacteria -- 1.2.2 Plant and animal cells -- 1.3 Biomaterials: soft strings and sheets -- 1.3.1 Soft filaments -- 1.3.2 Soft sheets -- 1.3.3 Soft vs. hard: entropy vs. energy -- 1.4 Forces inside and outside the cell -- Summary -- 2 Soft materials and fluids -- 2.1 Fluctuations at the cellular scale -- 2.2 Movement in a viscous fluid -- 2.2.1 Translational drag -- 2.2.2 Rotational drag -- 2.2.3 Reynolds number -- 2.3 Random walks -- 2.4 Diffusion -- 2.4.1 Densities and fluxes -- 2.5 Fluctuations and correlations -- Summary -- Problems -- Applications -- Formal development and extensions -- PART I RODS AND ROPES -- 3 Polymers -- 3.1 Polymers and simple biofilaments -- 3.2 Mathematical description of flexible rods -- 3.2.1 Arc length and curvature -- 3.2.2 Bending energy of a thin rod -- 3.2.3 Directional fluctuations and persistence length -- 3.3 Sizes of polymer chains -- 3.3.1 Ideal chains and filaments -- 3.3.2 Self-avoiding linear chains -- 3.3.3 Branched polymers -- 3.3.4 Collapsed chains -- 3.4 Entropic elasticity -- 3.4.1 Random chain in three dimensions -- 3.4.2 Entropic elasticity -- 3.4.3 Highly stretched chains -- 3.5 Buckling -- 3.6 Measurements of bending resistance -- 3.6.1 Measurements of persistence length -- 3.6.2 ξp and Young's modulus -- 3.6.3 Filament configurations in the cell -- 3.6.4 Filamentous cells -- Summary -- Problems -- Applications.
880 8 |6505-00|aFormal development and extensions -- 4 Complex filaments -- 4.1 The structure of complex filaments -- 4.2 Torsion, twist and writhe -- 4.2.1 Twist without curvature -- 4.2.2 Twist with curvature -- 4.2.3 Twist and writhe -- 4.3 Measurements of torsional rigidity -- 4.3.1 DNA -- 4.3.2 F-actin -- 4.3.3 Microtubules -- 4.3.4 Other filaments -- 4.4 Stretching of folded polymers -- (1) Spectrin -- (2) Ubiquitin -- (3) Tenascin -- (4) Titin -- 4.5 Protein and RNA folding -- concepts -- (1) α-helices -- (2) β-sheets -- 4.6 Models for polymer folding -- Summary -- Problems -- Applications -- Formal development and extensions -- 5 Two-dimensional networks -- 5.1 Soft networks in the cell -- 5.2 Elasticity in two dimensions -- 5.2.1 Deformations and the strain tensor -- 5.2.2 Forces and the stress tensor -- 5.2.3 Elastic moduli -- 5.2.4 Six-fold networks in 2D -- 5.2.5 Four-fold networks in 2D -- 5.2.6 Networks of springs -- 5.3 Isotropic networks -- 5.3.1 Six-fold spring networks under stress -- 5.3.2 Six-fold spring networks at non-zero temperature -- 5.4 Networks with low coordination number -- 5.5 Membrane-associated networks -- 5.5.1 Measured network elasticity -- 5.5.2 Interpretation of measurements -- Summary -- Problems -- Applications -- Formal development and extensions -- 6 Three-dimensional networks -- 6.1 Networks of biological rods and ropes -- 6.2 Elasticity in three dimensions -- 6.2.1 Strain and stress -- 6.2.2 Elastic moduli -- 6.2.3 Young's modulus and Poisson's ratio -- 6.2.4 Spring network with cubic symmetry -- 6.3 Entropic networks -- 6.3.1 Construction of random chain networks -- 6.3.2 Deformation of the network -- 6.3.3 Entropy change under deformation -- 6.3.4 Elastic moduli -- 6.4 Network percolation and failure -- 6.5 Semiflexible polymer solutions -- 6.5.1 Classification of polymer solutions -- 6.5.2 Storage and loss moduli.
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Staff View for: Mechanics of the cell