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Transgenesis and targeted mutagenesis in immunology /

edited by Horst Bluethmann, Pamela S. Ohashi.

Book Cover
Names: Ohashi, Pamela S. | Bluethmann, Horst
Published: San Diego : Academic Press, c1994.
Topics: Mice - Immunology. | Immunology - Animal models. | Transgenic mice. | Immune System. | Mice, Transgenic - Immunology. | Mutagenesis, Site-Directed. | Disease Models, animal.
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000 02270cam a2200361 a 4500
001 3643299
003 UIUdb
005 20020415165157.0
008 931103s1994 caua b 001 0 eng c
020 |a0121057607 (acid-free paper)
035 |a(OCoLC)ocm29361189
035 |9AYA-8260
050 00|aQR182.2.A54|bT73 1994
060 00|aQW 541|bT772 1994
069 0 |a9318244
082 00|a619/.93|220
245 00|aTransgenesis and targeted mutagenesis in immunology /|cedited by Horst Bluethmann, Pamela S. Ohashi.
260 |aSan Diego :|bAcademic Press,|cc1994.
300 |axx, 316 p. :|bill. ;|c24 cm.
504 |aIncludes bibliographical references and index.
505 0 |aTransgenic mouse models to study VDJ recombination -- Lymphocyte development and function in T cell receptor and RAG-1 mutant mice -- RAG-2 deficient blastocyst complementation -- Role of CD4 and CD8 in determining cell fate in the thymus -- T cell development in CD4, CD8 and p56 gene-targeted mice -- T cell tolerance in T cell receptor transgenic ipr/ipr mice -- Thymocyte selection and peripheral tolerance using the lymphocyte choriomeningitis virus as a model antigen -- Peripheral T cell tolerance: distinct levels and multistep mechanisms.
505 0 |aPeripheral tolerance and CD4⁺ T cells -- Studies of tolerance, inflammation and autoimmunity in transgenic mice -- Immunological studies utilizing cytokine transgenic mice -- Effect of MHC class II encoding transgenes on autoimmunity in nonobese diabetic mice -- Development and function of the immune system in mice with targeted disruption of the interleukin 2 gene -- Immune responses in interleukin 4-deficient mice -- Manipulation of transgene-encoded self-antigens to explore mechanisms of B cell tolerance -- Transgenic mouse model for peripheral B cell tolerance.
505 0 |aImmunobiology of MHC class I-deficient mice -- MHC class II mutant mice.
650 0|aMice|xImmunology.
650 0|aImmunology|xAnimal models.
650 0|aTransgenic mice.
650 2|aImmune System.
650 2|aMice, Transgenic|xImmunology.
650 2|aMutagenesis, Site-Directed.
650 2|aDisease Models, animal.
700 10|aOhashi, Pamela S.
700 10|aBluethmann, Horst

Staff View for: Transgenesis and targeted mutagenesis in